Glycoprotein IX (Platelet) (GP9) (Middle Region) Peptid
GP9
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN977575
Kurzübersicht für Glycoprotein IX (Platelet) (GP9) (Middle Region) Peptid (ABIN977575)
Target
CD42a (GP9)
(Glycoprotein IX (Platelet) (GP9))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- NSLQSVPPGA FDHLPQLQTL DVTQNPWHCD CSLTYLRLWL EDRTPEALLQ
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-GP9 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))
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Hintergrund
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This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.
Alias Symbols: CD42a, GPIX
Protein Interaction Partner: GP1BA,GP1BB
Protein Size: 177 -
Molekulargewicht
- 19 kDa
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Gen-ID
- 2815
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NCBI Accession
- NM_000174, NP_000165
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UniProt
- P14770
Target
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