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Glutamate Dehydrogenase 1 (GLUD1) (N-Term) Peptid

GLUD1 Reaktivität: Human Wirt: Synthetic BP, IHC, WB
Produktnummer ABIN977477

Kurzübersicht für Glutamate Dehydrogenase 1 (GLUD1) (N-Term) Peptid (ABIN977477)

Target

GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
  • Protein Region

    N-Term

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-GLUD1 antibody (Catalog #: ARP45708_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

    Hintergrund

    L-glutamate dehydrogenase (EC 1.4.1.3) has a central role in nitrogen metabolism in plants and animals. Glutamate dehydrogenase is found in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate. Glutamate, the main substrate of GLUD, is present in brain in concentrations higher than in other organs. In nervous tissue, GLUD appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification. L-glutamate dehydrogenase (EC 1.4.1.3) has a central role in nitrogen metabolism in plants and animals. Glutamate dehydrogenase is found in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate (Smith et al., 2001 [PubMed 11254391]). Glutamate, the main substrate of GLUD, is present in brain in concentrations higher than in other organs. In nervous tissue, GLUD appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification (Mavrothalassitis et al., 1988 [PubMed 3368458]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-51 M20867.1 1-51 52-3120 BC112946.1 16-3084

    Alias Symbols: GDH, GDH1, GLUD, MGC132003

    Protein Interaction Partner: DYNLL1,GLUD1,GOT2

    Protein Size: 558

    Molekulargewicht

    56 kDa

    Gen-ID

    2746

    NCBI Accession

    NM_005271, NP_005262

    UniProt

    P00367
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