gamma-Glutamyl Carboxylase (GGCX) (Middle Region) Peptid
GGCX
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
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- Target Alle GGCX Produkte
- GGCX (gamma-Glutamyl Carboxylase (GGCX))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-GGCX antibody (Catalog #: ARP44340_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GGCX (gamma-Glutamyl Carboxylase (GGCX))
- Hintergrund
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GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP, MIM 112260) and bone matrix protein (MGP, MIM 154870).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ26629, VKCFD1
Protein Interaction Partner: BGLAP,F10,F2,F7,F9,PROC
Protein Size: 758 - Molekulargewicht
- 87 kDa
- Gen-ID
- 2677
- NCBI Accession
- NM_000821, NP_000812
- UniProt
- P38435
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