Glucokinase (Hexokinase 4) Regulator (GCKR) (C-Term) Peptid
Kurzübersicht für Glucokinase (Hexokinase 4) Regulator (GCKR) (C-Term) Peptid (ABIN977331)
Target
Spezies
Quelle
Applikation
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Protein Region
- C-Term
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Sequenz
- PIALLSLLFR CSITEAQAHL AAAPSVCEAV RSALAGPGQK RTADPLEILE
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-GCKR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
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Hintergrund
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This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Alias Symbols: GKRP, FGQTL5
Protein Interaction Partner: GCK,GCK,TRAF2,UBC
Protein Size: 625 -
Molekulargewicht
- 68 kDa
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Gen-ID
- 2646
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NCBI Accession
- NM_001486, NP_001477
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UniProt
- Q14397
Target
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