Glucosidase, Beta, Acid (GBA) (C-Term) Peptid
GBA
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle GBA Produkte
- GBA (Glucosidase, Beta, Acid (GBA))
- Protein Region
- C-Term
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- EGSQRVGLVA SQKNDLDAVA LMHPDGSAVV VVLNRSSKDV PLTIKDPAVG
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-GBA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- GBA (Glucosidase, Beta, Acid (GBA))
- Hintergrund
-
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Alias Symbols: GBA1, GCB, GLUC
Protein Size: 536 - Molekulargewicht
- 59 kDa
- Gen-ID
- 2629
- NCBI Accession
- NM_000157, NP_000148
- UniProt
- P04062
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