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gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) Peptid

GABRA1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN977203
  • Target Alle GABRA1 Produkte
    GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
    Spezies
    Human
    Quelle
    • 7
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-GABRA1 antibody (Catalog #: ARP34977_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
    Synonyme
    ECA4 Peptide, EJM Peptide, EJM5 Peptide, zgc:153566 Peptide, Gabra-1 Peptide, gamma-aminobutyric acid type A receptor alpha1 subunit Peptide, gamma-aminobutyric acid (GABA) A receptor, alpha 1 Peptide, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 Peptide, gamma-aminobutyric acid receptor subunit alpha-1 Peptide, GABRA1 Peptide, Gabra1 Peptide, gabra1 Peptide, LOC100653509 Peptide
    Hintergrund
    GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.

    Alias Symbols: ECA4, EJM, EJM5

    Protein Interaction Partner: PPP3CA,PRKCD,PRKCG,PRKCD,PRKCG

    Protein Size: 456
    Molekulargewicht
    52 kDa
    Gen-ID
    2554
    NCBI Accession
    NM_000806, NP_000797
    UniProt
    P14867
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