Glucose 6-Phosphatase, Catalytic (G6PC) (N-Term) Peptid
G6PC
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN977184
Kurzübersicht für Glucose 6-Phosphatase, Catalytic (G6PC) (N-Term) Peptid (ABIN977184)
Target
G6PC
(Glucose 6-Phosphatase, Catalytic (G6PC))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-G6PC antibody (Catalog #: ARP44224_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
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Hintergrund
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G6PC hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum.It forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I (von Gierke disease). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: G6PT, GSD1a, MGC163350, GSD1, G6PC1
Protein Interaction Partner: FOXO1
Protein Size: 357 -
Molekulargewicht
- 40 kDa
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Gen-ID
- 2538
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NCBI Accession
- NM_000151, NP_000142
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UniProt
- P35575
Target
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