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Frizzled Family Receptor 4 (FZD4) (Middle Region) Peptid

FZD4 Reaktivität: Human Wirt: Synthetic BP, IHC, WB
Produktnummer ABIN977169

Kurzübersicht für Frizzled Family Receptor 4 (FZD4) (Middle Region) Peptid (ABIN977169)

Target

FZD4 (Frizzled Family Receptor 4 (FZD4))

Spezies

Human

Quelle

  • 8
Synthetic

Applikation

Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
  • Protein Region

    Middle Region

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-FZD4 antibody (Catalog #: ARP41266_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    FZD4 (Frizzled Family Receptor 4 (FZD4))

    Hintergrund

    FZD4 is a member of the frizzled family. Members of this family are seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: EVR1, FEVR, FZD4S, Fz-4, FzE4, GPCR, MGC34390, CD344

    Protein Interaction Partner: ARRB2,DLG1,DLG2,DLG4,DVL2,MAGI3,DLG4

    Protein Size: 537

    Molekulargewicht

    60 kDa

    Gen-ID

    8322

    NCBI Accession

    NM_012193, NP_036325

    UniProt

    Q9ULV1
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