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Forkhead Box O4 (FOXO4) (C-Term) Peptid

FOXO4 Reaktivität: Human, Maus Wirt: Synthetic BP, WB
Produktnummer ABIN977074
  • Target Alle FOXO4 Produkte
    FOXO4 (Forkhead Box O4 (FOXO4))
    Protein Region
    C-Term
    Spezies
    Human, Maus
    Quelle
    • 8
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    PPVMAGAPIP KVLGTPVLAS PTEDSSHDRM PQDLDLDMYM ENLECDMDNI
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-Foxo4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    FOXO4 (Forkhead Box O4 (FOXO4))
    Hintergrund
    Foxo4 is a transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. It down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. It represses smooth muscle cell differentiation by inhibiting the transcriptional coactivator activity of myocardin.

    Alias Symbols: Afxh, MGC117660, Mllt7, afx

    Protein Size: 505
    Molekulargewicht
    54 kDa
    Gen-ID
    54601
    NCBI Accession
    NM_001005872, NP_001005872
    UniProt
    Q99MK2
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