Forkhead Box A2 (FOXA2) (Middle Region) Peptid
Kurzübersicht für Forkhead Box A2 (FOXA2) (Middle Region) Peptid (ABIN976981)
Target
Spezies
Quelle
Applikation
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Protein Region
- Middle Region
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Sequenz
- SSGGKKTAPG SQASQAQLGE AAGSASETPA GTESPHSSAS PCQEHKRGGL
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Foxa2 Antibody(ARP37060_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FOXA2 (Forkhead Box A2 (FOXA2))
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Hintergrund
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Foxa2 is a transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues.Foxa2 is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites.Foxa2 binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. In embryonic development Foxa2 is required for notochord formation.Foxa2 is involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs.
Alias Symbols: HNF3-beta, HNF3beta, Hnf-3b, Hnf3b, Tcf-3b, Tcf3b
Protein Interaction Partner: Acadm,Acadvl,Gck,Hnf4a,Igfbp1,Pklr,Ucp2
Protein Size: 459 -
Molekulargewicht
- 48 kDa
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Gen-ID
- 15376
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NCBI Accession
- NM_010446, NP_034576
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UniProt
- P35583
Target
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