FK506 Binding Protein 3, 25kDa (FKBP3) Peptid
FKBP3
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle FKBP3 Produkte
- FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-FKBP3 antibody (Catalog #: ARP54612_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))
- Hintergrund
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FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Alias Symbols: FKBP-25, PPIase, FKBP-3, FKBP25
Protein Interaction Partner: CSNK2A1,CSNK2A2,CSNK2B,HDAC1,HDAC2,YY1,HDAC1,HDAC2,MDM2,MTA2,TP53,YY1
Protein Size: 224 - Molekulargewicht
- 25 kDa
- Gen-ID
- 2287
- NCBI Accession
- NM_002013, NP_002004
- UniProt
- Q00688
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