Fragile Histidine Triad (FHIT) (Middle Region) Peptid
FHIT
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN976850
Kurzübersicht für Fragile Histidine Triad (FHIT) (Middle Region) Peptid (ABIN976850)
Target
FHIT
(Fragile Histidine Triad (FHIT))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- VHVLPRKAGD FHRNDSIYEE LQKHDKEDFP ASWRSEEEMA AEAAALRVYF
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-FHIT Antibody(ARP51169_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FHIT (Fragile Histidine Triad (FHIT))
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Hintergrund
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This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: AP3Aase, FRA3B
Protein Interaction Partner: FDXR,FHIT,GSN,HSPD1,SRC,UBE2I,FHIT,UBE2I
Protein Size: 147 -
Molekulargewicht
- 17 kDa
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Gen-ID
- 2272
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NCBI Accession
- NM_002012, NP_002003
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UniProt
- P49789
Target
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