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Fibroblast Growth Factor 2 (Basic) (FGF2) (Middle Region) Peptid

FGF2 Reaktivität: Human Wirt: Synthetic WB, BP, IHC
Produktnummer ABIN976833

Kurzübersicht für Fibroblast Growth Factor 2 (Basic) (FGF2) (Middle Region) Peptid (ABIN976833)

Target

FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Spezies

Human

Quelle

  • 6
Synthetic

Applikation

Western Blotting (WB), Blocking Peptide (BP), Immunohistochemistry (IHC)
  • Protein Region

    Middle Region

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-FGF2 antibody (Catalog #: ARP42005_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

    Hintergrund

    The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: BFGF, FGFB, HBGF-2

    Protein Interaction Partner: NRP1,API5,CD44,CEP57,CSNK2A1,CSNK2A2,CSNK2B,CXCL13,FGF2,FGFBP1,FGFR1,FGFR3,FGFR4,FGFRL1,GPC3,GPC4,HSPG2,NRP1,PF4,PRMT1,PTX3,RPL6,RPS19,RPS6KA3,SDC1,SDC2,SDC3,VTN,CSNK2A1,CSNK2A2,CSNK2B,FGFBP1,FGFR1,GPC3,GPC4,RPL6,RPS19,SDC1,SDC2,SDC3,SDC4,VTN

    Protein Size: 288

    Molekulargewicht

    31 kDa

    Gen-ID

    2247

    NCBI Accession

    NM_002006, NP_001997

    UniProt

    P09038
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