Fas (TNFRSF6)-Associated Via Death Domain (FADD) Peptid
FADD
Reaktivität: Human, Maus
Wirt: Synthetic
BP, WB
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- Target Alle FADD Produkte
- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
- Spezies
- Human, Maus
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Fadd antibody (Catalog #: ARP30294_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
- Hintergrund
-
Fadd is apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
Alias Symbols: Mort1/FADD
Protein Interaction Partner: Nol3
Protein Size: 205 - Molekulargewicht
- 23 kDa
- Gen-ID
- 14082
- NCBI Accession
- NM_010175, NP_034305
- UniProt
- Q61160
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