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Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA) Peptid

ETFA Reaktivität: Human Wirt: Synthetic WB, BP
Produktnummer ABIN976460

Kurzübersicht für Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA) Peptid (ABIN976460)

Target

ETFA (Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA))

Spezies

Human

Quelle

  • 7
  • 3
Synthetic

Applikation

Western Blotting (WB), Blocking Peptide (BP)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-ETFA antibody (Catalog #: ARP54290_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    ETFA (Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA))

    Hintergrund

    ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids.ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: EMA, GA2, MADD

    Protein Interaction Partner: ETFB

    Protein Size: 333

    Molekulargewicht

    35 kDa

    Gen-ID

    2108

    NCBI Accession

    NM_000126, NP_000117

    UniProt

    P13804
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