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Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA) Peptid

ETFA Reaktivität: Human Wirt: Synthetic WB, BP
Produktnummer ABIN976459
  • Target Alle ETFA Produkte
    ETFA (Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA))
    Spezies
    Human
    Quelle
    • 7
    • 3
    Synthetic
    Applikation
    Western Blotting (WB), Blocking Peptide (BP)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-ETFA antibody (Catalog #: ARP54289_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ETFA (Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA))
    Hintergrund
    ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids.ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: EMA, GA2, MADD

    Protein Interaction Partner: ETFB

    Protein Size: 333
    Molekulargewicht
    35 kDa
    Gen-ID
    2108
    NCBI Accession
    NM_000126, NP_000117
    UniProt
    P13804
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