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Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6) (Middle Region) Peptid

ENPP6 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN976358

Kurzübersicht für Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6) (Middle Region) Peptid (ABIN976358)

Target

ENPP6 (Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6))

Spezies

Human

Quelle

  • 1
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-ENPP6 antibody (Catalog #: ARP53158_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    ENPP6 (Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6))

    Hintergrund

    ENPP6 is a choline-specific glycerophosphodiester phosphodiesterase. ENPP6 hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. ENPP6 hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. ENPP6 has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently.

    Alias Symbols: MGC33971, NPP6

    Protein Size: 440

    Molekulargewicht

    50 kDa

    Gen-ID

    133121

    NCBI Accession

    NM_153343, NP_699174

    UniProt

    Q6UWR7
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