Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2) (N-Term) Peptid
ENPP2
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN976357
Kurzübersicht für Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2) (N-Term) Peptid (ABIN976357)
Target
ENPP2
(Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- YTLATGLYPE SHGIVGNSMY DPVFDATFHL RGREKFNHRW WGGQPLWITA
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-ENPP2 Antibody(ARP44907_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))
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Hintergrund
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The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: ATX, ATX-X, FLJ26803, LysoPLD, NPP2, PD-IALPHA, PDNP2, AUTOTAXIN
Protein Size: 863 -
Molekulargewicht
- 95 kDa
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Gen-ID
- 5168
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NCBI Accession
- NM_001040092, NP_001035181
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UniProt
- Q13822
Target
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