E74 like ETS transcription factor 4 (Elf4) Peptid
Elf4
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle Elf4 Produkte
- Elf4 (E74 like ETS transcription factor 4 (Elf4))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-ELF4 antibody (Catalog #: ARP38028_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Elf4 (E74 like ETS transcription factor 4 (Elf4))
- Hintergrund
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ELF4 contains 1 ETS DNA-binding domain and belongs to the ETS family. It is transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. It transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. It acts synergistically with RUNX1 to transactivate the IL3 promoter and also transactivates the PRF1 promoter in natural killer (NK) cells. ELF4 plays a role in the development and function of NK and NK T-cells and in innate immunity.
Alias Symbols: MEF, ELFR
Protein Interaction Partner: FBXO4,FBXO7,PML,RUNX1,SKP2,UBB,RUNX1
Protein Size: 663 - Molekulargewicht
- 71 kDa
- Gen-ID
- 2000
- NCBI Accession
- NM_001421, NP_001412
- UniProt
- Q99607
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