Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (N-Term) Peptid
EIF3E
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN976223
Kurzübersicht für Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (N-Term) Peptid (ABIN976223)
Target
EIF3E
(Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-EIF3E antibody (Catalog #: ARP48175_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
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Hintergrund
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EIF3E belongs to the eIF-3 subunit E family.It is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. EIF3E is required for nonsense-mediated mRNA decay (NMD), It may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. The protein may interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
Alias Symbols: EIF3-P48, EIF3S6, INT6, eIF3-p46
Protein Interaction Partner: tax,BAT2,COPS6,COPS7A,COPS7B,COPS8,DDX24,EIF3C,EIF3L,EIF4ENIF1,EPAS1,GPAA1,GPBP1L1,HAP1,IFIT1,NDRG1,NSF,RUNDC3A,SMAD9,TRIM27,BAT2,CNTF,COPS6,CSN3,DDX24,EIF1B,EIF3A,EIF3F,EIF3H,EIF3L,GPAA1,GPBP1L1,HAP1,IFIT1,MAGED1,NSF,RGS2,RUNDC3A,SAP18,TRIM27,USP20
Protein Size: 445 -
Molekulargewicht
- 52 kDa
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Gen-ID
- 3646
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NCBI Accession
- NM_001568, NP_001559
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UniProt
- P60228
Target
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