Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1) (N-Term) Peptid
EEF1E1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN976149
Kurzübersicht für Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1) (N-Term) Peptid (ABIN976149)
Target
EEF1E1
(Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- IPVLQTNNGP SLTGLTTIAA HLVKQANKEY LLGSTAEEKA IVQQWLEYRV
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-EEF1E1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))
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Hintergrund
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This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.
Alias Symbols: AIMP3, P18
Protein Interaction Partner: ATM,ATR,ATM,ATR
Protein Size: 174 -
Molekulargewicht
- 19 kDa
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Gen-ID
- 9521
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NCBI Accession
- NM_004280, NP_004271
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UniProt
- O43324
Target
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