This is a synthetic peptide designed for use in combination with anti-Ecsit Antibody(ARP37175_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Nur für Forschungszwecke einsetzbar
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Final peptide concentration is 1 mg/mL in PBS.
Avoid repeated freeze-thaw cycles.
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
(ECSIT Homolog (ECSIT))
Sitpec, ECSIT signalling integrator, Ecsit
Ecsit is required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase. Ecsit is an adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1.Ecsit promotes proteolytic activation of MAP3K1. Ecsit is involved in the BMP signaling pathway. Ecsit is required for normal embryonic development.
Alias Symbols: Sitpec
Protein Interaction Partner: Irak1,Map3k1,SMURF1,TRAF6,Traf6