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Deltex Homolog 2 (DTX2) Peptid

DTX2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN976019
  • Target Alle DTX2 Produkte
    DTX2 (Deltex Homolog 2 (DTX2))
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-DTX2 antibody (Catalog #: ARP43285_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    DTX2 (Deltex Homolog 2 (DTX2))
    Hintergrund
    DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

    Alias Symbols: KIAA1528, MGC71098, RNF58

    Protein Interaction Partner: DTX1,DTX2,DTX3,HPCAL1,HPCAL4,NCALD,NCS1,NOTCH1,PLSCR1,RBPMS,RFX6,RHOXF2,TRIP13,UBE2D4,UBQLN4,VSNL1,HPCAL1,HPCAL4,NCALD,NCS1,PLSCR1,RBPMS,RFX6,RHOXF2,SFN,TRIP13,UBE2D4,VSNL1

    Protein Size: 575
    Molekulargewicht
    62 kDa
    Gen-ID
    113878
    NCBI Accession
    NM_001102596, NP_001096066
    UniProt
    Q6XM87
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