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Dystrobrevin, beta (DTNB) Peptid

DTNB Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN976017

Kurzübersicht für Dystrobrevin, beta (DTNB) Peptid (ABIN976017)

Target

Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-DTNB antibody (Catalog #: ARP46310_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))

    Hintergrund

    DTNB is dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin.This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Alias Symbols: MGC17163, MGC57126

    Protein Interaction Partner: BEGAIN,C1orf182,CCDC85B,DMD,DTNB,DTNBP1,HMG20A,KIF5A,NUP62,PPFIBP2,PRTFDC1,SNTG1,SNTG2,TRAF2,UTRN,BEGAIN,C1orf182,CCDC85B,DMD,HMG20A,KIF5A,KIF5B,NUP62,PPFIBP2,PRTFDC1,SNTA1,TRAF2

    Protein Size: 567

    Molekulargewicht

    64 kDa

    Gen-ID

    1838

    NCBI Accession

    NM_033148, NP_149160

    UniProt

    O60941
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