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Diphthamide Biosynthesis Protein 2 (DPH2) Peptid

DPH2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN975968

Kurzübersicht für Diphthamide Biosynthesis Protein 2 (DPH2) Peptid (ABIN975968)

Target

DPH2 (Diphthamide Biosynthesis Protein 2 (DPH2))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-DPH2 antibody (Catalog #: ARP51958_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    DPH2 (Diphthamide Biosynthesis Protein 2 (DPH2))

    Hintergrund

    This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: DPH2L2

    Protein Size: 489

    Molekulargewicht

    52 kDa

    Gen-ID

    1802

    NCBI Accession

    NM_001384, NP_001375

    UniProt

    Q9BQC3
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