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Deoxyribonuclease II beta (DNASE2B) (Middle Region) Peptid

DNASE2B Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN975930

Kurzübersicht für Deoxyribonuclease II beta (DNASE2B) (Middle Region) Peptid (ABIN975930)

Target

DNASE2B (Deoxyribonuclease II beta (DNASE2B))

Spezies

Human

Quelle

  • 7
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-DNASE2B antibody (Catalog #: ARP42597_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    DNASE2B (Deoxyribonuclease II beta (DNASE2B))

    Hintergrund

    DNASE2B shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this protein is restricted to the salivary gland and lungs. The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.

    Alias Symbols: DLAD

    Protein Size: 153

    Molekulargewicht

    18 kDa

    Gen-ID

    58511

    NCBI Accession

    NM_058248, NP_490649

    UniProt

    Q5VXD0
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