Dickkopf Homolog 1 (DKK1) Peptid
DKK1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Kurzübersicht für Dickkopf Homolog 1 (DKK1) Peptid (ABIN975815)
Target
DKK1
(Dickkopf Homolog 1 (DKK1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-DKK1 antibody (Catalog #: ARP48015_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Dickkopf Homolog 1 (DKK1) peptide
DKK1 Reaktivität: Human, Rind (Kuh), Hund, Schwein, Ratte Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DKK1 (Dickkopf Homolog 1 (DKK1))
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Hintergrund
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DKK1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
Alias Symbols: DKK-1, SK
Protein Interaction Partner: CTNNB1,KREMEN1,LRP5,LRP6,MDFI,SMAD9,CORO1A,LRP6,MDFI
Protein Size: 266 -
Molekulargewicht
- 26 kDa
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Gen-ID
- 22943
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NCBI Accession
- NM_012242, NP_036374
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UniProt
- O94907
Target
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