Diaphanous Homolog 1 (DIAPH1) (C-Term) Peptid
Kurzübersicht für Diaphanous Homolog 1 (DIAPH1) (C-Term) Peptid (ABIN975792)
Target
Spezies
Quelle
Applikation
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Protein Region
- C-Term
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Sequenz
- TGVMDSLLEA LQSGAAFRRK RGPRQANRKA GCAVTSLLAS ELTKDDAMAA
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-DIAPH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DIAPH1 (Diaphanous Homolog 1 (DIAPH1))
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Hintergrund
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This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: DFNA1, DIA1, DRF1, FLJ25265, LFHL1, hDIA1
Protein Interaction Partner: CENPA,PKD2,BAIAP2,CDC7,CENPA,PAX6,PKD2,PRPF40A,RAC1,RHOA,RHOC,XPO6,APBB1,GAS7,NEDD4,PRPF40A,RHOA,SRGAP2,TCERG1,UBC,WBP4,XPO6
Protein Size: 1272 -
Molekulargewicht
- 141 kDa
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Gen-ID
- 1729
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NCBI Accession
- NM_005219, NP_005210
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UniProt
- O60610
Target
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