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ATP-Dependent RNA Helicase A (DHX9) Peptid

DHX9 Reaktivität: Human Wirt: Synthetic BP, IHC, WB
Produktnummer ABIN975790

Kurzübersicht für ATP-Dependent RNA Helicase A (DHX9) Peptid (ABIN975790)

Target

DHX9 (ATP-Dependent RNA Helicase A (DHX9))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-DHX9 antibody (Catalog #: ARP36343_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    DHX9 (ATP-Dependent RNA Helicase A (DHX9))

    Hintergrund

    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DHX9 is a DEAD box protein with RNA helicase activity. It may participate in melting of DNA:RNA hybrids, such as those that occur during transcription, and may play a role in X-linked gene expression.DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein with RNA helicase activity. It may participate in melting of DNA:RNA hybrids, such as those that occur during transcription, and may play a role in X-linked gene expression. It contains 2 copies of a double-stranded RNA-binding domain, a DEXH core domain and an RGG box. The RNA-binding domains and RGG box influence and regulate RNA helicase activity.

    Alias Symbols: DDX9, LKP, NDH II, NDHII, RHA, NDH2

    Protein Interaction Partner: AKAP8L,BRCA1,DDX20,DHX9,GEMIN4,GTF2B,HDLBP,ILF3,JUN,KHDRBS1,MBD2,MGEA5,NXF1,PCNA,POLR2A,PRMT1,PRPF8,RELA,SIP1,SMN2,SMN2,SNRPB,SNRPB2,SRPK1,SSRP1,STAU1,TBP,TOP2A,AKAP8L,ARHGDIA,BRCA1,CNBP,DDX20,GEMIN4,GTF2B,HDLBP,HINFP,JUN,KHDRBS1,LYAR,MBD2,MEPCE,NXF1,PRMT1,RELA,SIP1,SMN1,TBP,TOP2A,XRCC5,XRCC6

    Protein Size: 1279

    Molekulargewicht

    141 kDa

    Gen-ID

    1660

    NCBI Accession

    NM_001357, NP_001348

    UniProt

    Q08211
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