Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) Peptid
DEAF1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN975714
Kurzübersicht für Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) Peptid (ABIN975714)
Target
DEAF1
(Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-DEAF1 antibody (Catalog #: ARP39468_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Aufreinigung
- Purified
-
-
-
-
Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Konzentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
-
Hintergrund
-
DEAF1 down-regulates transcription of those genes by binding to sequence with multiple copies of TTC[CG]G present in their own promoter and that of the HNRPA2B1 gene. DEAF1 binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. DEAF1 activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.
Alias Symbols: SPN, NUDR, ZMYND5
Protein Interaction Partner: DEAF1,ASCC2,INTS1,ASCC2,LMO4
Protein Size: 565 -
Molekulargewicht
- 59 kDa
-
Gen-ID
- 10522
-
NCBI Accession
- NM_021008, NP_066288
-
UniProt
- O75398
Target
-
Sie sind hier:
