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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) Peptid

DDX21 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN975677

Kurzübersicht für DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) Peptid (ABIN975677)

Target

DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-DDX21 antibody (Catalog #: ARP36375_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))

    Hintergrund

    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX21 encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.

    Alias Symbols: GUA, GURDB, RH-II/GU, RH-II/GuA

    Protein Interaction Partner: JUN,PIAS1,JUN,LYAR,PSTPIP1,RRP1B,RTCD1,Rrp1b,SMNDC1

    Protein Size: 783

    Molekulargewicht

    86 kDa

    Gen-ID

    9188

    NCBI Accession

    NM_004728, NP_004719

    UniProt

    Q9NR30
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