Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-DCN antibody (Catalog #: ARP48199_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
Decorin (DCN)
Hintergrund
DCN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. This protein and biglycan are thought to be the result of a gene duplication. DCN is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.
Alias Symbols: CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B
Protein Interaction Partner: AHSG,C1QA,COL14A1,COL1A1,COL1A2,COL4A1,COL4A3,COL4A4,COL4A5,COL4A6,COL5A1,DPT,EGFR,ELN,FBN1,FLNA,FN1,MMP2,MMP3,MMP7,PLA2G2A,SFTPD,TGFB1,THBS1,TNF,WISP1,AHSG,C1QA,COL14A1,COL6A1,EGFR,ELN,FLNA,PLA2G2A,SFTPD,TGFB1,TGFB2,TNF