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Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) (Middle Region) Peptid

DAAM1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN975574
  • Target Alle DAAM1 Produkte
    DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 2
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-DAAM1 antibody (Catalog #: ARP55131_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
    Synonyme
    1700066F09Rik Peptide, 2310028E21Rik Peptide, AI503486 Peptide, E130308H01 Peptide, mKIAA0666 Peptide, daam-1 Peptide, xdaam1 Peptide, daam1 Peptide, DAAM1 Peptide, DKFZp468D0524 Peptide, daam1l Peptide, fc83b10 Peptide, si:ch211-87i20.1 Peptide, wu:fc83b10 Peptide, dishevelled associated activator of morphogenesis 1 Peptide, dishevelled associated activator of morphogenesis 1 S homeolog Peptide, dishevelled associated activator of morphogenesis 1a Peptide, dishevelled associated activator of morphogenesis 1b Peptide, DAAM1 Peptide, Daam1 Peptide, daam1.S Peptide, daam1a Peptide, daam1 Peptide, daam1b Peptide
    Hintergrund
    Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein.Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.

    Alias Symbols: FLJ41657, KIAA0666

    Protein Interaction Partner: DVL1,DVL2,RHOA

    Protein Size: 1078
    Molekulargewicht
    123 kDa
    Gen-ID
    23002
    NCBI Accession
    NM_014992, NP_055807
    UniProt
    Q9Y4D1
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