Cathepsin E (CTSE) (N-Term) Peptid
CTSE
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN975440
Kurzübersicht für Cathepsin E (CTSE) (N-Term) Peptid (ABIN975440)
Target
Cathepsin E (CTSE)
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- SLKKKLRARS QLSEFWKSHN LDMIQFTESC SMDQSAKEPL INYLDMEYFG
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CTSE Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Cathepsin E (CTSE)
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Hintergrund
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The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.
Alias Symbols: CATE
Protein Interaction Partner: A2M,BAG6,CTSE,EDN3,EMG1,INS,BAG6
Protein Size: 363 -
Molekulargewicht
- 40 kDa
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Gen-ID
- 1510
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NCBI Accession
- NM_148964, NP_683865
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UniProt
- P14091
Target
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