Cystatin B (Stefin B) (CSTB) (N-Term) Peptid
CSTB
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle CSTB Produkte
- CSTB (Cystatin B (Stefin B) (CSTB))
- Protein Region
- N-Term
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- ADQVRSQLEE KENKKFPVFK AVSFKSQVVA GTNYFIKVHV GDEDFVHLRV
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CSTB Antibody(ARP59177_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- CSTB (Cystatin B (Stefin B) (CSTB))
- Hintergrund
-
CSTB is a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in CSTB gene are responsible for the primary defects in patients with progressive myoclonic epilepsy a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy.
Alias Symbols: CST6, EPM1, PME, STFB, ULD, EPM1A
Protein Interaction Partner: CTSB,CTSD,CTSH,CTSL1,CST3,CTSB,CTSH,VHL
Protein Size: 98 - Molekulargewicht
- 11 kDa
- Gen-ID
- 1476
- NCBI Accession
- NM_000100, NP_000091
- UniProt
- P04080
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