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Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1) (Middle Region) Peptid

CSH1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN975363

Kurzübersicht für Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1) (Middle Region) Peptid (ABIN975363)

Target

CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))

Spezies

Human

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    LFDHAMLQAH RAHQLAIDTY QEFRLEDGSR RTGQILKQTY SKFDTNSHNH

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-CSH2 Antibody(ARP52403_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))

    Hintergrund

    The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, while the ratio of 1 to 2 increases by term. Structural and expression differences provide avenues for developmental regulation and tissue specificity.

    Alias Symbols: CS-2, CSB, hCS-B

    Protein Interaction Partner: POLR2A

    Protein Size: 122

    Molekulargewicht

    14 kDa

    Gen-ID

    1443

    NCBI Accession

    NM_022645, NP_072171

    UniProt

    B1A4H9
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