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Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1) (Middle Region) Peptid

CSH1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN975363
  • Target Alle CSH1 Produkte
    CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    LFDHAMLQAH RAHQLAIDTY QEFRLEDGSR RTGQILKQTY SKFDTNSHNH
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-CSH2 Antibody(ARP52403_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))
    Hintergrund
    The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, while the ratio of 1 to 2 increases by term. Structural and expression differences provide avenues for developmental regulation and tissue specificity.

    Alias Symbols: CS-2, CSB, hCS-B

    Protein Interaction Partner: POLR2A

    Protein Size: 122
    Molekulargewicht
    14 kDa
    Gen-ID
    1443
    NCBI Accession
    NM_022645, NP_072171
    UniProt
    B1A4H9
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