Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) Peptid
KCNIP3
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
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- Target Alle DREAM (KCNIP3) Produkte
- DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CSEN antibody (Catalog #: ARP31932_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
- Hintergrund
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CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.
Alias Symbols: CSEN, DREAM, KCHIP3
Protein Interaction Partner: CASP3,CD177,CREB1,CREM,PSEN1,PSEN2,CD177,CREB1,CREM,CRK,PSEN1,PSEN2
Protein Size: 256 - Molekulargewicht
- 29 kDa
- Gen-ID
- 30818
- NCBI Accession
- NM_013434, NP_038462
- UniProt
- Q9Y2W7
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