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V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (Middle Region) Peptid

CRKL Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN975318
  • Target Alle CrkL (CRKL) Produkte
    CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 2
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    RSSPHGKHGN RNSNSYGIPE PAHAYAQPQT TTPLPAVSGS PGAAITPLPS
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-CRKL Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
    Synonyme
    CRKL Peptide, wu:fa55g05 Peptide, wu:fj60e01 Peptide, zgc:63469 Peptide, 1110025F07Rik Peptide, AA589403 Peptide, AI325100 Peptide, Crkol Peptide, CRK like proto-oncogene, adaptor protein Peptide, v-crk avian sarcoma virus CT10 oncogene homolog-like Peptide, CRKL Peptide, crkl Peptide, Crkl Peptide
    Hintergrund
    CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fibroblast transformation by BCR-ABL. In addition, CRKL has oncogenic potential.

    Alias Symbols: -

    Protein Size: 303
    Molekulargewicht
    34 kDa
    Gen-ID
    1399
    NCBI Accession
    NM_005207, NP_005198
    UniProt
    P46109
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