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V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (Middle Region) Peptid
CRKL
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktdetails
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Target
Alle CrkL (CRKL) Produkte
CrkL (CRKL)
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
Protein Region
Middle Region
Spezies
Human
Quelle
Alle Wirte für CrkL Peptide
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Sequenz
RSSPHGKHGN RNSNSYGIPE PAHAYAQPQT TTPLPAVSGS PGAAITPLPS
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-CRKL Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Aufreinigung
Purified
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigendetails
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Target
CrkL (CRKL)
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
Synonyme
CRKL Peptide, wu:fa55g05 Peptide, wu:fj60e01 Peptide, zgc:63469 Peptide, 1110025F07Rik Peptide, AA589403 Peptide, AI325100 Peptide, Crkol Peptide, CRK like proto-oncogene, adaptor protein Peptide, v-crk avian sarcoma virus CT10 oncogene homolog-like Peptide, CRKL Peptide, crkl Peptide, Crkl Peptide
Hintergrund
CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fibroblast transformation by BCR-ABL. In addition, CRKL has oncogenic potential. Alias Symbols: - Protein Size: 303
Molekulargewicht
34 kDa
Gen-ID
1399
NCBI Accession
NM_005207 , NP_005198
UniProt
P46109
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Peptide
CrkL
V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (Middle Region) Peptid (ABIN975318)