Cysteine-Rich Secretory Protein 1 (CRISP1) (N-Term) Peptid
CRISP1
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle CRISP1 Produkte
- CRISP1 (Cysteine-Rich Secretory Protein 1 (CRISP1))
- Protein Region
- N-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- ARIFSKYCDM TESNPLERRL PNTFCGENMH MTSYPVSWSS VIGVWYSEST
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CRISP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CRISP1 (Cysteine-Rich Secretory Protein 1 (CRISP1))
- Hintergrund
-
Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. CRISP1 is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head where it plays a role at fertilization in sperm-egg fusion through complementary sites localized on the egg surface.
Alias Symbols: AEGL1, ARP, CRISP-1, HSCRISP1D, HSCRISP1G, HUMARP
Protein Size: 249 - Molekulargewicht
- 27 kDa
- Gen-ID
- 167
- NCBI Accession
- NM_001131, NP_001122
- UniProt
- P54107
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