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Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (Middle Region) Peptid

CPT1A Reaktivität: Human Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN975267
  • Target Alle CPT1A Produkte
    CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-CPT1A antibody (Catalog #: ARP44796_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
    Hintergrund
    The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation.The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: CPT1, CPT1-L, L-CPT1

    Protein Interaction Partner: BCL2

    Protein Size: 756
    Molekulargewicht
    86 kDa
    Gen-ID
    1374
    NCBI Accession
    NM_001031847, NP_001027017
    UniProt
    P50416
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