Cortistatin (CORT) (N-Term) Peptid
CORT
Reaktivität: Human
Wirt: Synthetic
WB, BP
Produktnummer ABIN975212
Kurzübersicht für Cortistatin (CORT) (N-Term) Peptid (ABIN975212)
Target
CORT
(Cortistatin (CORT))
Spezies
Human
Quelle
Synthetic
Applikation
Western Blotting (WB), Blocking Peptide (BP)
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Protein Region
- N-Term
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Sequenz
- MPLSPGLLLL LLSGATATAA LPLEGGPTGR DSEHMQEAAG IRKSSLLTFL
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CORT Antibody(ARP59541_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Cortistatin (CORT) peptide (Ovalbumin)
CORT Reaktivität: Human Wirt: Synthetic WB, Imm, SDS
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CORT (Cortistatin (CORT))
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Hintergrund
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This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739.
Alias Symbols: CST-14, CST-17, CST-29
Protein Interaction Partner: GHSR,MRGPRX2,SSTR1,SSTR2,SSTR3,SSTR4,SSTR5,SSTR1,SSTR2,SSTR3,SSTR4,SSTR5
Protein Size: 155 -
Molekulargewicht
- 2 kDa
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Gen-ID
- 1325
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NCBI Accession
- NM_001302, NP_001293
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UniProt
- O00230
Target
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