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Coatomer Protein Complex, Subunit alpha (COPA) Peptid

COPA Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN975184
  • Target Alle COPA Produkte
    COPA (Coatomer Protein Complex, Subunit alpha (COPA))
    Spezies
    Human
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-COPA antibody (Catalog #: ARP51893_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    COPA (Coatomer Protein Complex, Subunit alpha (COPA))
    Synonyme
    COPA Peptide, DDBDRAFT_0189693 Peptide, DDBDRAFT_0233797 Peptide, DDB_0189693 Peptide, DDB_0233797 Peptide, DKFZp469O221 Peptide, AU040324 Peptide, xenin Peptide, HEP-COP Peptide, cb281 Peptide, fb13c12 Peptide, wu:fb13c12 Peptide, coatomer protein complex subunit alpha Peptide, WD40 repeat-containing protein Peptide, Coatomer subunit alpha Peptide, coatomer protein complex, subunit alpha Peptide, coatomer protein complex subunit alpha L homeolog Peptide, COPA Peptide, copA Peptide, cgd8_860 Peptide, Chro.80105 Peptide, AFUA_3G08840 Peptide, copa Peptide, Copa Peptide, copa.L Peptide
    Hintergrund
    In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone.In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.

    Alias Symbols: FLJ26320, HEP-COP

    Protein Interaction Partner: COPE,SACM1L,ARCN1,ARFGAP1,COPB2,COPE,MTNR1B,PDGFRB,SACM1L,SLC25A11,STX8,TMED2,ARFGAP1,BET1L,COPB1,COPB2,COPE,PDGFRB,SLC25A11,USP49

    Protein Size: 1224
    Molekulargewicht
    135 kDa
    Gen-ID
    1314
    NCBI Accession
    NM_004371, NP_004362
    UniProt
    P53621
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