Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) Peptid
CHRNA7
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN974956
Kurzübersicht für Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) Peptid (ABIN974956)
Target
CHRNA7
(Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CHRNA7 antibody (Catalog #: ARP35418_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7))
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Hintergrund
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The protein encoded by CHRNA7 displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia.
Alias Symbols: NACHRA7, CHRNA7-2
Protein Interaction Partner: ADCY6,APP,PIK3R1,ADCY6,FYN
Protein Size: 502 -
Molekulargewicht
- 56 kDa
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Gen-ID
- 1139
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NCBI Accession
- NM_000746, NP_000737
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UniProt
- P36544
Target
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