Checkpoint Kinase 1 (CHEK1) Peptid
CHEK1
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
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- Target Alle CHEK1 Produkte
- CHEK1 (Checkpoint Kinase 1 (CHEK1))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CHEK1 antibody (Catalog #: ARP32589_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CHEK1 (Checkpoint Kinase 1 (CHEK1))
- Hintergrund
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CHEK1 is required during normal S phase to avoid aberrantly increased initiation of DNA replication, thereby protecting against DNA breakage. Its expression is dispensable for somatic cell death and critical for sustaining G2 DNA damage checkpoint.
Alias Symbols: CHK1
Protein Interaction Partner: E2F1,E2F4,ATR,CDC25A,CDC25A,CDC25C,RAD51,RELA,AATF,AKT1,ATM,ATR,BLM,CDC25A,CDC25B,CDC25C,CLSPN,CSNK2B,CUL1,CUL4A,HSP90AA1,MDM4,RAD51,RELA,SMAD4,TLK1,TP53,UBB,XIAP,XRCC6,YWHAG,ATM,ATR,BLM,CDC25A,CDC25B,CDC25C,CDKN1A,CLSPN,CSNK2A1,MCD1,MSH2,PRKDC,SFN,TIMELESS,TP53,TP53BP1,XIAP,XRCC5,XRCC6
Protein Size: 476 - Molekulargewicht
- 54 kDa
- Gen-ID
- 1111
- NCBI Accession
- NM_001274, NP_001265
- UniProt
- O14757
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