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Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) Peptid

CHAF1B Reaktivität: Human Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN974889
  • Target Alle CHAF1B Produkte
    CHAF1B (Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B))
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-CHAF1B antibody (Catalog #: ARP45827_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CHAF1B (Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B))
    Hintergrund
    Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. CHAF1B corresponds to the p60 subunit and is required for chromatin assembly after replication. CHAF1B is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.

    Alias Symbols: CAF-1, CAF-IP60, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7

    Protein Interaction Partner: HIST1H3E,ASF1A,ASF1B,CDK1,CDK2,CHAF1A,HIST1H3B,RBBP4,ASF1A,ASF1B,BAZ1B,CBX5,CHAF1A

    Protein Size: 559
    Molekulargewicht
    61 kDa
    Gen-ID
    8208
    NCBI Accession
    NM_005441, NP_005432
    UniProt
    Q13112
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