CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (C-Term) Peptid
CEBPA
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN974818
Kurzübersicht für CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (C-Term) Peptid (ABIN974818)
Target
CEBPA
(CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequenz
- ASGGSGAGKA KKSVDKNSNE YRVRRERNNI AVRKSRDKAK QRNVETQQKV
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CEBPA Antibody(ARP57938_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
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Hintergrund
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CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Alias Symbols: C/EBP-alpha, CEBP
Protein Interaction Partner: LTF,NCOA6,PIAS1,ATF2,CDK2,CDK4,CDKN1A,CDKN3,CDX1,CEBPA,CEBPB,CEBPD,CREBBP,CTNNB1,DBP,EP300,GATA2,GSK3B,HNF1A,MSX2,MYC,NCOA6,NFYA,NR3C1,PIAS1,RB1,RBL1,RFC1,RUNX1,SOX10,SOX8,SPI1,SUMO3,ACTN1,AR,ATF2,Atf2,CDK2,CDK4,CEBPB,CHD1,CTNNB1,EDF1,ESR1,GRIN3A,JUN,MAF,
Protein Size: 358 -
Molekulargewicht
- 37 kDa
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Gen-ID
- 1050
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NCBI Accession
- NM_004364, NP_004355
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UniProt
- P49715
Target
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