CDT1
(Chromatin Licensing and DNA Replication Factor 1 (CDT1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-CDT1 antibody (Catalog #: ARP46350_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
CDT1
(Chromatin Licensing and DNA Replication Factor 1 (CDT1))
Hintergrund
CDT1 cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. It binds DNA in a sequence-, strand-, and conformation-independent manner and is a potential oncogene.
Alias Symbols: DUP, RIS2
Protein Interaction Partner: DDB1,CCNA2,CDC5L,CDC6,CDK1,CDK2,CDT1,GMNN,MCM6,ORC1L,ORC2L,PCNA,SKP2,UBB,ANAPC5,ANAPC7,BAZ1B,CDC20,CDC23,CDC6,CUL1,E2F1,FZR1,GMNN,GRWD1,KPNA2,KPNB1,MCM4,MCM6,MCM7,NPM1,PCNA,SKP2,SMARCA5,TOP1,TOP2A