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Cyclin-Dependent Kinase 7 (CDK7) (Middle Region) Peptid

CDK7 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN974779
  • Target Alle CDK7 Produkte
    CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-CDK7 antibody (Catalog #: P100995_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
    Hintergrund
    CDK7 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: CAK1, CDKN7, MO15, STK1, p39MO15, HCAK

    Protein Interaction Partner: CDK2,CDK6,RARA,THRA,VDR,AR,BRCA1,CCNH,CDK1,CDK2,CDK7,E2F1,ERCC2,ERCC3,ESR1,GTF2H1,GTF2H2,GTF2H5,LASP1,MCM7,MNAT1,NEK6,PCGF6,RARA,THRA,VDR,AR,CCNH,CCT2,CDC37,CUX1,E2F1,ERCC3,ERCC5,ESR1,GTF2H1,GTF2H2,GTF2H3,GTF2H4,GTF2H5,HDAC2,HNRNPU,HSP90AB1,KIAA1967,MCM7,MED21,MNAT1,MTA1,POLR2A,RUVBL2,SUPT5H,TCEA1,TP53

    Protein Size: 346
    Molekulargewicht
    39 kDa
    Gen-ID
    1022
    NCBI Accession
    NM_001799, NP_001790
    UniProt
    P50613
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