This is a synthetic peptide designed for use in combination with anti-CDK5 antibody (Catalog #: AVARP03025_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
CDK5
(Cyclin-Dependent Kinase 5 (CDK5))
Hintergrund
CDK5 is probably involved in the control of the cell cycle. It interacts with D1 and D3-type G1 cyclins. The protein can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. And it is also thought to interacts with p35 which activates the kinase.
Alias Symbols: PSSALRE
Protein Interaction Partner: CDK5R1,CDK5R1,ABL1,ACTN1,AMPH,APP,C1orf61,CABLES1,CABLES2,CCND2,CCNG1,CDC37,CDK16,CDK5,CDK5R1,CDK5R2,CDK5RAP1,CDKN1B,CHN1,CSNK1D,DAB1,DCX,DNM1,ERBB3,EZR,FSD1,FYN,GAK,GRIN2A,GSK3B,MAP2K1,MAPK10,MAPT,MAPT,MAPT,MEF2A,NDEL1,NES,PAK1,PCNA,PIP5K1C,PPP1R1B,PPP1R2,PSEN1,PTPN2,PURA,SET,SRC,STX1A,STXBP1,SYN1,SYNJ1,TP53,WASF1,BRCA1,CABLES2,CCND2,CDK16,CDK5R1,CDK5RAP2,GAK,LMTK2,NDEL1,NES,PAK1,PARK2,STX1A,STXBP1,TP53