P-Cadherin (CDH3) Peptid
CDH3
Reaktivität: Human
Wirt: Synthetic
BP, IHC, WB
Produktnummer ABIN974754
Kurzübersicht für P-Cadherin (CDH3) Peptid (ABIN974754)
Target
P-Cadherin (CDH3)
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CDH3 antibody (Catalog #: ARP45170_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- P-Cadherin (CDH3)
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Hintergrund
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CDH3 is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Its gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in its gene have been associated with congential hypotrichosis with juvenile macular dystrophy.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
Alias Symbols: CDHP, HJMD, PCAD
Protein Interaction Partner: CDH3,CTNNA1,CTNNB1,CTNND1,CD2AP,CDH1,CDH3,CTNNA1,CTNNB1,CTNND1,JUP,NPHS1
Protein Size: 829 -
Molekulargewicht
- 91 kDa
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Gen-ID
- 1001
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NCBI Accession
- NM_001793, NP_001784
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UniProt
- P22223
Target
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